Chromosome Y

1.1. Group composition

Participating country(ies): Iran
Head: Hosseini Salekdeh

1.2. Missing proteins

Protein evidence according to NeXtProt for Chromosome Y:
Protein evidence status in text format is available here.

1.3. Bioinformatics protocols

1.4. Analytical protocols

1.5. Biological projects

1.6. Biomaterials

1.7. Data sets

1.8. Special expertise

1.9. Major achievements


  • Meyfour A, Pooyan P, Pahlavan S, Rezaei-Tavirani M, Gourabi H, Baharvand H, Salekdeh GH. Chromosome-Centric Human Proteome Project Allies with Developmental Biology: a Case Study of the Role of Y chromosome Genes in Organ Development. J Proteome Res. 2017 Sep 15. doi: 10.1021/acs.jproteome.7b00446. PuMed PMID: 28914051.
  • Meyfour A, Ansari H, Pahlavan S, Mirshahvaladi S, Rezaei-Tavirani M, Gourabi H, Baharvand H, Salekdeh GH. Y Chromosome Missing Protein, TBL1Y, May Play an Important Role in Cardiac Differentiation. J Proteome Res. 2017 Sep 13. doi: 10.1021/acs.jproteome.7b00391. PuMed PMID: 28853286.


  • Jangravi Z, Tabar MS, Mirzaei M, Parsamatin P, Vakilian H, Alikhani M, Shabani M, Haynes PA, Goodchild AK, Gourabi H, Baharvand H, Salekdeh GH. Two Splice Variants of Y Chromosome-Located Lysine-Specific Demethylase 5D Have Distinct Function in Prostate Cancer Cell Line (DU-145). J Proteome Res. 2015 Sep 4;14(9):3492-502. doi: 10.1021/acs.jproteome.5b00333. Epub 2015 Aug 10. PubMed PMID: 26215926.
  • Ahmadi Rastegar D, Sharifi Tabar M, Alikhani M, Parsamatin P, Sahraneshin Samani F, Sabbaghian M, Sadighi Gilani MA, Mohammad Ahadi A, Mohseni Meybodi A, Piryaei A, Ansari-Pour N, Gourabi H, Baharvand H, Salekdeh GH. Isoform-Level Gene Expression Profiles of Human Y Chromosome Azoospermia Factor Genes and Their X Chromosome Paralogs in the Testicular Tissue of Non-Obstructive Azoospermia Patients. J Proteome Res. 2015 Sep 4;14(9):3595-605. doi: 10.1021/acs.jproteome.5b00520. PubMed PMID: 26162009.
  • Vakilian H, Mirzaei M, Sharifi Tabar M, Pooyan P, Habibi Rezaee L, Parker L, Haynes PA, Gourabi H, Baharvand H, Salekdeh GH. DDX3Y, a Male-Specific Region of Y Chromosome Gene, May Modulate Neuronal Differentiation. J Proteome Res. 2015 Sep 4;14(9):3474-83. doi: 10.1021/acs.jproteome.5b00512. PubMed PMID: 26144214.


  • Jangravi Z, Alikhani M, Arefnezhad B, Sharifi Tabar M, Taleahmad S, Karamzadeh R, Jadaliha M, Mousavi SA, Ahmadi Rastegar D, Parsamatin P, Vakilian H, Mirshahvaladi S, Sabbaghian M, Mohseni Meybodi A, Mirzaei M, Shahhoseini M, Ebrahimi M, Piryaei A, Moosavi-Movahedi AA, Haynes PA, Goodchild AK, Nasr-Esfahani MH, Jabbari E, Baharvand H, Sedighi Gilani MA, Gourabi H, Salekdeh GH. A fresh look at the male-specific region of the human Y chromosome. J Proteome Res. 2013 Jan 4;12(1):6-22. doi: 10.1021/pr300864k. PubMed PMID: 23253012.

1.10. The neXt-MP50 challenge