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Time
SUNDAY (9/30/2018)

Pre-Congress Day

Time
THURSDAY (10/4/2018)

HPP Post-Congress Day
07:30–08:50
Room: Gardenia 2
B/D-HPP EC Meeting
Room: Banda Sea 2
C-HPP EC Meeting
08:15–08:30
Coffee
09:00–09:15
HPP Overview
Gil Omenn. Presentation is available here
(Room: Banda Sea 1)
08:30–9:30
What Exciting Prospects Lie Ahead?
Moderated by Rob Moritz, supported by Jennifer Watson 4-5 min presentations: Jenny van Eyk, Ileana Cristea, Ferdinando Cerciello, Jochen Schwenk, Chris Overall plus five more young investigators being identified: Lightning presentations with general participation.
09:15–10:15
HPP Reports (12 min each)
Chair: Gil Omenn

1. C-HPP (Young-Ki Paik). Presentation is available here.
2. B/D-HPP (Fernando J. Corrales). Presentation is available here.
3. Knowledge Base Pillar (Eric Deutsch & Lydie Lane). Presentation is available here
4. MS Pillar (Sue Weintraub). Presentation is available here.
5. Pathology Pillar (Dan Chan/Ed Nice)
9:30–12:10
HPP Town Hall Meeting
Deep Dive on HPP Goals, Strategy and Deliverables for the next 3 years, and Potential for Big International Translational Projects.
Chairs: Fernando Corrales & Young-Ki Paik

• 09:30-10:10 How can we accelerate identification of the remaining 2186 PE2,3,4 Missing Proteins? Siqi Liu, Eric Deutsch, Lydie Lane, Jochen Schwenk, Nino Bandeira, Chris Overall.
• 10:10-10:50 Identification and functional annotation of PTMs.
Chair: Alexey Nesvizhskii. Ultrafast Methods for Detection of PTMs (Alexey Nesvizhskii)
Results from the 96-phosphopeptide HPP sample community analysis (representative of MS Resource Pillar)
Roles of PTMs in Cardiovascular Disorders (Peggi Angel)
Proteogenomics; splice variants; proteoforms (Neil Kelleher). This presentation is available here.
10:15–12:00
Featured HPP Session
Chair: Mark Baker


1. C-HPP 2.0 Discussion (Chris Overall; 20 min). Presentation is available here.
2. B/D-HPP, Prioritization of Popular Proteins (Kun-Hsing Yu; 20 min)
3. Antibody Validation Initiative (52 min) (Jochen Schwenk, Mathias Uhlen (Peter Nilsson), Cecilia Lindskog Bergström, Heng Zhu, Lydie Lane, Cristina Al-Khalili Szigyarto)
• 10:50-11:30 Functional Studies: Protein-protein interactions; Single-Cell Analyses
How are protein-protein interaction data being incorporated by neXtProt for missing proteins and functionally unannotated proteins? (Lydie Lane)
Methods and applications of single-cell analyses of proteins (Bernd Bodenmiller)
• 11:30-12:10 Translational/Clinical Proteomics Strategies & Priorities
How can we more effectively incorporate proteomics in clinical research across many specialties? (Steve Pennington). This presentation is available here.
What lessons can be learned from international collaborations for Cancer Proteomics and applied for other disease categories? (Henry Rodriguez). This presentation is available here.
12:00–13:00
Lunch and Discussion.
12:10–13:10
Lunch, with HPP Senior Scientific Advisory Board Discussion Outline of Two-Year Strategic Plan for the HPP (Mark Baker). This presentation is available here
Lead Discussants: Cathy Costello, John Yates (Gil Omenn, moderator)
General Discussion
13:00–13:40
Round Table 1
Major Public DBs and MS Data Analysis

(Lydie Lane, Eric Deutsch)

Leaders of neXtProt, PeptideAtlas, and ProteomeXchange will highlight developments at each DB and invite comments and inquiries from end users.
13:00–14:00
Emerging Technologies for the HPP.
(Chairs: Rob Moritz and John Yates).
Using CRISPR/Cas9 genome-editing techniques to modify human iPSC and differentiated cells for Hemophilia B treatment (Bonghee Lee). This presentation is available here.
Proteogenomics: Revisiting human protein-coding genome annotation (Janne Lehtiö. This presentation is available here.
13:40–14:20
Round Table 2
Exploring the Undiscovered “Dark” Proteome

(Young-Ki Paik/Fernando Corrales)

• Accelerating progress to identify and annotate PE2-4 Missing Proteins
• Generating functional annotations for uPE1 Proteins
• Mobilizing/connecting C-HPP and B/D-HPP teams
14:00–15:00
What are the Grand Challenges for the Entire Field of Proteomics
Inspirational speaker: Mike Snyder. Presentation is available here.
General discussion
14:20–15:40
Two Breakout Sessions
B/D-HPP PI Meeting
(Banda Sea 1) and C-HPP PIC Meeting (Banda Sea 2)


B/D-HPP: Open session on Popular Proteins with specific presentations by the PIs of the following initiatives: Rheumatoid Diseases, PediOme, Glycoproteomics, Kidney/Urine-HPP, Diseasome
C-HPP: organizational and scientific strategies (PIs of C-HPP teams)
Part I: Report Session
Part 2: Business Session
Part 3: Election & Free Discussion

Invited Talk: J. Eugene Lee: Ab measurement standardization, KRISS, Korea)
neXt-CP50: Resources
21st C-HPP Workshop in St. Malo
22nd C-HPP Workshop in St. Petersburg
Emerging issues
15:00–15:30
Session devoted to Gil Omenn’s Leadership of the HPP with Light Reception (Chair: Mark Baker).
15:40–17:00
Reception (everyone invited)
HUPO Council Meeting for HUPO Councilors
(Baker, Pennington, Overall, Weintraub, Martens, Hui Zhang, Lane)

Appendix 3

20th C-HPP Workshop, Appendix 3

HPP Track M-W of Concurrent/Parallel Sessions within HUPO2018

October 1-3, 2018

The HPP has organized 6 thematic sessions for the Mon-Wed HPP concurrent tracks. Chair and Co-Chair are presently known. Each will present two invited speakers and 5 speakers selected from abstracts submitted. On each of the 3 days of the HUPO2018 Congress, there will be one HPP parallel session in the morning (10:30am) and one parallel session in the afternoon (2:00pm).

HPP: PARTNERING WITH PATHOLOGY TOWARD PRECISION MEDICINE (MonD am)

Session Chairs: Daniel Chan and Ed Nice

Invited Speakers

  • Stephen Pennington (University College Dublin)
  • Peter Stewart (Royal Prince Alfred Hospital Sydney)
  • Elena Ponomarenko (Institute of Biomedical Chemistry, Russia)
  • Tadashi Yamamoto (Niigata University, Japan)
  • Michael Roehrl (Memorial Sloan Kettering, USA)
  • Danni Li (University of Minnesota, USA)
  • Ruth Hüttenhain (University of California, San Franciso, USA)

HPP TARGETING THE PROTEOME IN WOMEN'S HEALTH (MonD pm)

Session Chairs: Burcu Ayoglu and Jenny Van Eyk

Invited Speaker

  • Tony Whetton
  • Katelyn C Cook (Princeton University, USA)
  • Yuan Zhang (Binzhou Medical University)
  • Tanja Meyer (University Medicine Greifswald, Germany)

HPP: METABOLIC REMODELING AND HUMAN DISEASE (TuesD am)

Session Chairs: Ferdinando Cerciello and Fernando Corrales

Invited Speakers

  • Cristina Alonso (OWL Metabolomics, Spain))
  • Matthias Mann (Max Planck Institute for Biochemistry, Germany)
  • Michelle Hill (QIMR Berghofer Medical Research Institute and University of Queensland Diamantina Institute, Australia)
  • Fernando Corrales (Nacional de Biotecnología, CSIC; CIBEREHD, Spain)
  • Ling Lin (Fudan University, China)
  • Felix Elortza (CIC bioGUNE and ProteoRed-ISCIII, Spain)

HPP: HARNESSING THE IMMUNE SYSTEM TO FIGHT DISEASE (TuesD pm)

Session Chairs: Arie Admon and Ileana Cristea

Invited Speaker

  • Etienne Caron (ETH Zurich, Switzerland)
  • Aleksandra Nita-Lazar (National Institute for Allergy and Infectious Disease, NIH, USA)
  • Arie Admon (Technion-Israel Inst. of Tech, Israel)
  • Laura Murray (Princeton University, USA)
  • Subhra Chakraborty (National Institute of Plant Genome Research, India)
  • Rebekah L. Gundry (Medical College of Wisconsin, USA)
  • Pierre Thibault (Universite de Montreal, Canada)

HPP: HUMAN CHEMOSENSATION: OLFACTION, TASTE, AND SIGHT (WedD am)

Session Chairs: Mark Baker and Jong Shin Yoo

Invited Speakers

  • Andreas Keller (Columbia University, USA)
  • Daniella Reed (Monell Institute, USA)
  • Jing Gao (Shanghai Institute of Materia Medica)
  • Meleha Ahmad (Wilmer Eye Institute, USA)
  • Subash Adhikari (Macquarie University, Australia)
  • Heeyoun Hwang (Korea Basic Science Institute, South Korea)
  • Speaker Roundtable

HPP: UNRAVELING TISSUE PATHOLOGY THROUGH CELL SAMPLING (WedD pm)

Session Chair: Emma Lundberg

Invited Speakers

  • Cecilia L. Bergstrom (Uppsala University, Sweden)
  • Bernd Bodenmiller (University of Zurich, Switzerland)
  • David Muddiman (North Carolina State University)
  • Florian Meier (Max Planck Institute of Biochemistry, Germany)
  • TBD
  • TBD
  • TBD


Click here to go the overview of C-HPP activities in HUPO 2018, Orlando.