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18th  C-HPP Workshop, Santiago de Compostela, Spain, June 16-17, 2018

19th C HPP Symposium PROGRAM 14
 

Organized by

Fernando J. Corrales, Concha Gil and Young-Ki Paik.

 

19th  C-HPP Symposium

Santiago de Compostela, Spain

Venue: Faculty of Medicine, University of Santiago de Compostela: In the heart of the old city, close to Hotel Monumento San Francisco (EuPA meeting venue).

Saturday, June 16th

8:00h-8:20h Registration.

8:20h-8:30h Welcome Message. Fernando J. Corrales.

8:30h-9:00h The Human Proteome Project. Gil Omenn. This presentation in pdf format is available here.

9:00h-9:20h C-HPP: Progress Update and Future Direction: Young-Ki Paik (C-HPP Chair). This presentation in pdf format is available here.

9:20h-11:00h MP success and new strategies Red team (Chris Overall).

  • neXt-MP50 Challenge: Update (20 min). Chris Overall. Canada Research Chair in Protease Proteomics and Systems Biology. Life Sciences Institute. Canada.
  • Update on the deciphering of the testicular germ cell proteome (20 min). Charles Pineau. Research Director Inserm. Rennes, France. This presentation in pdf format is available here.
  • The proteome of human cerebrospinal fluid and the identification of missing proteins (10 min). Charlotte Macron. Nestlé Institute of Health Sciences SA. Lausanne, Switzerland. This presentation in pdf format is available here.
  • Short oral C-HPP group 2 (10 min). Christoph Borchers. UVic–Genome BC Proteomics Centre. This presentation in pdf format is available here.
  • New Workflow for Identification of Native Peptides in Urine: From sample preparation and Ion mobility TOF MS to Bioinformatics (10 min). Tadashi Yamamoto. Biofluid Biomarker Center, Niigata University, Japan.
  • Identification of missing proteins in mesenchymal stem cells derived from fat tissue and umbilical cord (10 min). Miguel Marcilla. National Center of Biotechnology-CSIC. Madrid, Spain. This presentation in pdf format is available here.
  • Discussion (20 min).

11:00h-11:30h Coffee break.

11:30h-13:30h Bioinformatics, Green team (Lydie Lane).
Update on the Status of Target Proteins --MPs, uPE1, smORFs, lncRNAs and others. This presentation in pdf format is available here.

  • Introduction (10 min). Lydie Lane. SIB-Swiss Institute of Bioinformatics.
  • Re-using and integrating public proteomics data to improve our knowledge of the human proteome (20 min). Juan A. Vizcaino. ProteomeXchange. EMBL-EBI. This presentation in pdf format is available here.
  • Keynote presentation 2 (20 min). Jong Shin Yoo. Korea Basic Science Institute. This presentation in pdf format is available here.
  • Action plan to decipher functions of Chr18 encoded proteins in the frame of neXt-CP50 Challenge (15 min). Elena Ponomarenko. Department for Bioinformatics. Institute of Biomedical Chemistry, Moscow, IBMC. This presentation in pdf format is available here.
  • Assessment of sample preparation bias in mass spectrometry-based proteomic (15 min). Peter Horvatovich. University of Groningen, The Netherlands. This presentation in pdf format is available here.
  • Discussion (40 min).

13:30h-15:00h Lunch break.

15:00h-17:00h neXt-CP50 Challenge: functional annotation, Blue team (Young-Ki Paik).

  • uPE1 Study Examples by Chr 13 Group. Young-Ki-Paik. This presentation in pdf format is available here.
  • Proteomics and metabolomics signatures of Zika congenital syndrome (20 min). Gilberto Domont. Institute of Chemistry, Universidade Federal do Rio de Janeiro. This presentation in pdf format is available here.
  • Combining bioinformatics and experimental methods to discover the function of poorly characterized human proteins - lessons from the CALIPHO project (20 min). Lydie Lane. SIB-Swiss Institute of Bioinformatics, University of Geneva, Switzerland. This presentation in pdf format is available here.
  • Sensitivity and specificity of mass-spectrometric proteomic technologies as factors determining the prospects for the CHPP project (10 min). Alexander Archakov. Institute of Biomedical Chemistry, Moscow, IBMC. This presentation in pdf format is available here.
  • Splice variants in Biology & Disease: Chromosome 12 and Beyond (10 min). Ravi Sirdeshmukh. Institute of Bioinformatics, Discoverer, ITPL. Bangalore, India.
  • Short oral C-HPP group 3 (10 min). Andrea Urbani. University of Rome “Tor Vergata”
  • Short oral C-HPP (10min). Ghasem Hosseini Salekdeh.
  • Deciphering Functional roles of missing proteins by Comprehensive integration of affinity proteomics, MS/MS & RNA-sequencing datasets in Chronic Lymphocytic Leukemia tumor B cells and healthy B cell subpopulations in the context of the Chromosome-Centric Human Proteome Project (10 min). Manuel Fuentes. Center for Cancer Research, University of Salamanca-CSIC.
  • Discussion (30 min)

17:00h-19:00h C-HPP EC meeting.

EuPA and C-HPP dinner.

Sunday, June 17th

9:00h-10:45h Young Investigators session.

  • Proteogenomics: Combining Next Generation Sequencing and Mass Spectrometry in Candida albicans (12+3 Q&A min). Mónica Franch. National Center of Biotechnology-CSIC. Madrid, Spain. 
  • Speaker 2 (12+3 Q&A min). Seul-Ki Jeong. YPRC. Yonsei Proteome Research Center. Seoul, Korea. This presentation in pdf format is available here.
  • Differential Immune Recognition of the Candida albicans yeast and Hyphal cell surface Proteomes in invasive Candidiasis (12+3 Q&A min). Aida Pitarch. Complutense University of Madrid, Spain.
  • Identification and characterization of missing proteins from human chromosome 9 (12+3 Q&A min). Yong-In Kim. Korea Research Institute of Standards and Science. This presentation in pdf format is available here.
  • Proteins Involved in RNA Splicing, Proteins synthesis and apoptosis are differentially abundant in Macrophages after interacting with Candida albicans (12+3 Q&A min). Catarina Oliveira. Complutense University of Madrid, Spain.
  • Speaker 6 (12+3 Q&A min). Heeyoun Hwang. Korea Basic Science Institute, KBSI.
  • Gene Editing for neXt-CP50 and neXt-MP50 challenges (12+3 Q&A min). Katerina Poverennaya. Institute of biomedical chemistry, Moscow, Russia. This presentation in pdf format is available here.


10:45h-11:15h Coffee break

11:15h-13:30h Long-term plans and directions for C-HPP (Young-Ki Paik, Christoph M. Overall).

  • Re-structuring C-HPP Teams for Phase II (2019-)
  • Strategies for the identification of MPs (Using info available on public proteome databases, proteogenomics, proteoforms, small ORFs, etc.).
  • Strategies for the functional annotation of Dark Proteome (MPs, uPE1, smORFs and lncRNA proteins) (Russian team proposal, and others).
  • Synergies and interactions across C-HPP and B/D-HPP groups (samples, data sharing…).
  • Other issues

13:30h-14:00h Next C-HPP meetings and other business.

  • 2018 JPR SI Update Christoph M. Overall.
  • 2018 HUPO Congress Workshop Plans Young-Ki Paik.
  • 2019 C-HPP Workshop Plans in St. Malo (Charles Pineau).