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SUN, Oct. 5%%%10:00-16:00, Rm D MON, Oct 6%%%8:00 - 9:20 Room C TUES, Oct 7%%%8:00 - 9:20 Exhibit Hall WED, SEPT 8%%%8:00 - 9:20 Room C
HPP General Investigators Meeting


(Chaired by Gil Omenn)


a. Overview of Progress,
b. Metrics, and Publications from the HPP
c. B/D-HPP Highlights,
d. C-HPP Highlights.
e. Update of HPP Metrics
f. Bioinformatics discussions and standardized re-analyses of major datasets of four major publications in 2014:
g. Discussion over working lunch about inter-relationships across HPP components and bioinformatics approaches.
h. Antibody and MS Resource Pillars
i. SSAB Panel, overview, strategic comments from SSAB members
j. Town Hall Meeting Open Forum – on B/D- and C-HPP Collaboration
k. Meeting of SSAB with l. HPP-EC for feedback.

Details in Appendix 1
C-HPP (Part 1)

● New Technology
(Chaired by Bill Hancock)


a. SRM measurement of missing proteins

b. RNA analysis, including predicting when transcript forms protein

c. Integration of RNA-Seq and proteomics

d. Approaches to ASV and SNV characterization such as down top MS, adoption of protein chemistry methods

e. Identification of protein families and sharing of specific data across chromosome families, integrated proteome browser

Details in Appendix 2
C-HPP (Part 2)

● Poster Session
(Chaired by Gyorgy Marko-Varga)


Poster Awards (Cash Prize and Award Certificate) will be given to


Total 10 Best Outstanding Poster Presenters


● It is required to load the poster no later than 5 pm, Monday. In addition to the C-HPP subjects (e.g., mapping missing proteins, ASV, PTM on each chromosome), any papers related to common technology or resources for C-HPP can also be presented. All eligible presenters should be one of the associated members of C-HPP consortium as of Sept 1, 2014.

Further Information in Appendix 3
C-HPP (Part 3)

● PIC Meeting
(Chaired by Young-Ki Paik)


● Topics: Metrics for success, elections, individual PI updates and Meeting Plans for 2015-2018


Details in Appendix 4

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HPP Plenary Session

● 15:00 - 16:50 pm

Room A

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Oct 9, Thursday

Segovia Meeting

Appendix 5

Appendix 2

C-HPP Meeting (Part 1): New Technology

Monday, October 6, 2014: 08:00 - 09:20 Rm C


Chaired by Bill Hancock

Invited Speakers: Confirmed as of 9/8/2014
Robert Moritz; Christoph Borchers; Ravi Sirdeshmukh; Siqi Liu; Gyorgy Marko-Varga

a) SRM measurement of missing proteins (8.05 to 8.20), Christoph Borchers, Rob Moritz, Ulrike Yassene, Alex Archakov. This presenation is available here.

b) Integration of RNA-Seq with proteomics, control of when transcript forms protein (8.25 to 8.45), Siqi Liu, Carol Nillsson , Ravi Sirdeshmukh

c) Approaches to ASV and SNV characterization (8.50 to 9.05), Gil Omenn, Akhilesh Pandey

d) Identification of protein families, integrated HPP browser (9.05 to 9.20), Lydie Lane, Dong Li, Ed Nice.Presentation of Lydie Lane and Dong li Lydie and Dong.pdf. Presenation of Ed Nice on "Antibody-Based Strategies for Detection of Missing Proteins" here.

Click here to go the overview of C-HPP activities in Madrid.